Pharmaceutical production and packaging

Dealing with humidity
in pharmaceutical
production and packaging

Pharmaceuticals operations require stringent control of every aspect of production and packaging. Airborne moisture is crucial here, because it has big effects on hygiene compliance, powder characteristics, product specifications, packaging and much else. You can easily find yourself confronted with:


  • Hygroscopic ingredients clumping together and congealing, resulting in processing glitches and equipment blockages
  • Bacterial activity as a result of uncontrolled moisture, impacting product and packaging quality and creating hygiene compliance concerns
  • Difficulties with documentation and regulatory approvals
  • Unscheduled production stoppages and high maintenance costs that limit your output and impact your profit margins


pharmaceutical production of capsules

Reducing inconsistencies in production conditions

Inconsistent conditions create problems

Uncontrolled or fluctuating levels of airborne moisture, often stemming from changes in weather and season, are renowned for giving rise to significant problems in many key processes involved in the production and packaging of pharmaceuticals.

Uncontrolled levels of moisture tend to encourage bacterial activity, and inconsistent conditions resulting from the natural humidity variations in the ambient air make it extremely difficult to maintain the kinds of consistent, meticulously controlled conditions essential for pharmaceutical-standard hygiene, and for all the documentation and regulatory approvals associated with pharmaceuticals production.

Humid air also makes hygroscopic ingredients clump together and congeal, resulting in processing glitches and equipment blockages, as well as impacting overall production efficiency. The resulting unscheduled stoppages and high maintenance costs limit your output as well as eating into profit margins.

Undesirable humidity will often also cause damage and spoilage to both packaging and product once it’s exited the production setups.

Full control counts

Controlled humidity enables you to establish – and maintain – exactly appropriate environments for manufacturing, packaging and storing pharmaceutical products – and their ingredients – that are hygroscopic and/or humidity-sensitive in other ways. This boosts quality and reduces risk at every stage of your pharmaceuticals production setup, regardless of configuration

Cotes adsorption dehumidifiers are the easiest and most cost-effective way to remove undesirable and uncontrolled airborne moisture from any pharmaceuticals production or packaging facility. This enables you to maintain consistent, controlled specifications, regardless of season, weather and other factors that might influence the relative humidity of the surrounding air.

Cotes solutions enable you to achieve and maintain relative humidity levels as low as 20%, using only a bare minimum of energy inputs

How you benefit

  • End-to-end consistency in your production and packaging processes, regardless of seasonal changes, weather and other phenomena
  • Less risk of powder clumping, blockages and waste, resulting in better control of key processes and lower maintenance costs
  • Greater output and better profitability, because of fewer production glitches and less downtime
  • Easier, more effective quality management, as is essential in the pharmaceuticals industry
  • Better hygiene compliance, thanks to end-to-end control of humidity conditions

How Cotes solutions stand out

Cotes solutions for tackling uncontrolled humidity in pharmaceutical production and packaging operations are
  • Capable of removing uncontrolled humidity from very large volumes of air
  • Exceptionally reliable, to minimise levels of risk in production
  • Available with advanced monitoring and control systems for maximum flexibility
  • Available with a Cotes energy recovery module to minimise energy consumption
  • Available with special air cooling systems to achieve exceptionally low relative humidities

Related industries

More about controlling humidity in pharmaceutical production
and packaging from Anders Kjeldgaard +45 2294 3303